The mission of this website is to make information on the Children at High and Low Risk for Depression Study readily available to the general
public and to the research community. The study, which is one of the only longitudinal, multi-generational studies of major depression, has made
important contributions to the understanding of the etiology of depression and its transmission in families over a period of 27 years.
On this website, there will be available a complete history of the study which includes key findings, a thorough description of the methodology
including number of participants in each wave and data collected, a list of publications with links to PDF versions, as well as comprehensive
information regarding de-identified data available to qualified and approved researchers.
What's New?
The Children at High and Low Risk Study is approaching its 30th consecutive year of NIMH funding and is planning on continuing to collect
additional clinical, genetic, EEG, and MRI data. ...More>>
About the Study
The Children at High and Low Risk for Depression study is multigenerational and longitudinal. The study design is a
retrospective cohort. ...More>>
Study History
The sample now includes 4 generations grandparents (G1), parents (G2), grandchildren (G3), and great-grandchildren(G4) and consists of families at
high or low risk for depression based on the depression status of the original sample (G1). ...More>>